Advances in the Prevention of Bone Bridge Formation after Epiphyseal Injury

• 1、Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, 430071

Abstract：The epiphyseal plate, also known as the growth plate, is the layered cartilage that connects the epiphyseal to the epiphyseal. The longitudinal growth of bone is the result of the growth of epiphyseal chondrocytes and endochondral ossification. The epiphyseal plate has the function of growing bone, but it is also the weakest link in the process of bone growth. It can cause damage due to trauma, tumor, radiation and bacterial infection. After the epiphyseal plate injury, vessels respectively form side branches which will extend to the epiphyseal defect area, forming the fiber vessel bridge, which eventually leads to the formation of the bone bridge. After the formation of the bone bridge, some or all of the epiphyseal plate may be closed early, resulting in bone growth disorder or disorder, which may result in limb angulation and/or shortening. The clinical treatment of epiphyseal plate injury in children is mainly to prevent the formation of bone bridge, but the effect is not ideal. This review focuses on the mechanism of bone bridge formation after epiphysis injury and the research progress of prevention of bone bridge formation.

Keywords： eiphyseal plate injury review bone bridge research progress?????